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No lethal dose The LD50 of DSIP has never been determined because it has never been possible to kill an animal regardless of the dose administered

Stimulation of IR upregulates both mitogen-activated protein (MAP)/extracellular signal-regulated kinase and phosphoinositide 3-kinases/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) signaling pathways and subsequently leading to inhibiting of apoptosis and promoting cell migration and proliferation [33]

Overview of metallothionein